"Clinical Cancer Genomics Laboratory, City of Hope Comprehensive Cance - ClinVar

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 1174604	NM_007294.4(BRCA1):c.5306dup (p.Tyr1769Ter)	BRCA1 (Y1722* +3 more)	Duplication (frameshift variant +2 more)	Breast-ovarian cancer, familial, susceptibility to, 1	GLikely pathogenic
Select item 1174603	NM_007294.4(BRCA1):c.4821del (p.Ala1608fs)	BRCA1 (A1561fs +3 more)	Deletion (frameshift variant +1 more)	Breast-ovarian cancer, familial, susceptibility to, 1	GPathogenic/Likely pathogenic
Select item 1174602	NM_007294.4(BRCA1):c.4645_4646dup (p.Thr1550fs)	BRCA1 (T1503fs +3 more)	Duplication (frameshift variant +1 more)	Breast-ovarian cancer, familial, susceptibility to, 1 +1 more	GPathogenic/Likely pathogenic
Select item 1174600	NM_007294.4(BRCA1):c.3359_3360insG (p.Val1120_Asn1121insTer)	BRCA1, LOC126862571	Insertion (frameshift variant +1 more)	Hereditary breast ovarian cancer syndrome +2 more	GPathogenic/Likely pathogenic
Select item 1174601	NG_005905.2:g.(141497_143462)_(154111_154610)dup	BRCA1	Duplication	Breast-ovarian cancer, familial, susceptibility to, 1	GLikely pathogenic
Select item 1174599	NG_005905.2:g.(92714_93868)_(173690_?)del	BRCA1	Deletion	Breast-ovarian cancer, familial, susceptibility to, 1	GLikely pathogenic
Select item 1174598	NG_005905.2:g.(111529_113027)_(147057_150288)del	BRCA1	Deletion	Breast-ovarian cancer, familial, susceptibility to, 1	GLikely pathogenic

ClinVar